M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00002 Glycolysis, core module involving three-carbon compounds
M00003 Gluconeogenesis, oxaloacetate => fructose-6P
M00004 Pentose phosphate pathway (Pentose phosphate cycle)
M00005 PRPP biosynthesis, ribose 5P => PRPP
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate
M00009 Citrate cycle (TCA cycle, Krebs cycle)
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
M00012 Glyoxylate cycle
M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA
M00014 Glucuronate pathway (uronate pathway)
M00015 Proline biosynthesis, glutamate => proline
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
M00017 Methionine biosynthesis, apartate => homoserine => methionine
M00018 Threonine biosynthesis, aspartate => homoserine => threonine
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
M00020 Serine biosynthesis, glycerate-3P => serine
M00021 Cysteine biosynthesis, serine => cysteine
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate
M00023 Tryptophan biosynthesis, chorismate => tryptophan
M00024 Phenylalanine biosynthesis, chorismate => phenylalanine
M00025 Tyrosine biosynthesis, chorismate => tyrosine
M00026 Histidine biosynthesis, PRPP => histidine
M00027 GABA (gamma-Aminobutyrate) shunt
M00028 Ornithine biosynthesis, glutamate => ornithine
M00029 Urea cycle
M00030 Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00031 Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
M00032 Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
M00033 Ectoine biosynthesis, aspartate => ectoine
M00034 Methionine salvage pathway
M00035 Methionine degradation
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA
M00037 Melatonin biosynthesis, tryptophan => serotonin => melatonin
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
M00039 Monolignol biosynthesis, phenylalanine/tyrosine => monolignol
M00040 Tyrosine biosynthesis, prephanate => pretyrosine => tyrosine
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
M00044 Tyrosine degradation, tyrosine => homogentisate
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate
M00047 Creatine pathway
M00048 Inosine monophosphate biosynthesis, PRPP + glutamine => IMP
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
M00050 Guanine ribonucleotide biosynthesis IMP => GDP,GTP
M00051 Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP
M00053 Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP
M00055 N-glycan precursor biosynthesis
M00056 O-glycan biosynthesis, mucin type core
M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone
M00060 Lipopolysaccharide biosynthesis, KDO2-lipid A
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P
M00063 CMP-KDO biosynthesis
M00064 ADP-L-glycero-D-manno-heptose biosynthesis
M00065 GPI-anchor biosynthesis, core oligosaccharide
M00066 Lactosylceramide biosynthesis
M00067 Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid
M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer
M00072 N-glycosylation by oligosaccharyltransferase
M00073 N-glycan precursor trimming
M00074 N-glycan biosynthesis, high-mannose type
M00075 N-glycan biosynthesis, complex type
M00076 Dermatan sulfate degradation
M00077 Chondroitin sulfate degradation
M00078 Heparan sulfate degradation
M00079 Keratan sulfate degradation
M00080 Lipopolysaccharide biosynthesis, inner core => outer core => O-antigen
M00081 Pectin degradation
M00082 Fatty acid biosynthesis, initiation
M00083 Fatty acid biosynthesis, elongation
M00085 Fatty acid biosynthesis, elongation, mitochondria
M00086 beta-Oxidation, acyl-CoA synthesis
M00087 beta-Oxidation
M00088 Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone
M00089 Triacylglycerol biosynthesis
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE
M00094 Ceramide biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway
M00096 C5 isoprenoid biosynthesis, non-mevalonate pathway
M00097 beta-Carotene biosynthesis, GGAP => beta-carotene
M00098 Acylglycerol degradation
M00099 Sphingosine biosynthesis
M00100 Sphingosine degradation
M00101 Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol
M00102 Ergocalciferol biosynthesis
M00103 Cholecalciferol biosynthesis
M00104 Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
M00106 Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate
M00107 Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
M00112 Tocopherol/tocotorienol biosynthesis
M00113 Jasmonic acid biosynthesis
M00114 Ascorbate biosynthesis, plants, glucose-6P => ascorbate
M00115 NAD biosynthesis, aspartate => NAD
M00116 Menaquinone biosynthesis, chorismate => menaquinone
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate => ubiquinone
M00118 Glutathione biosynthesis, glutamate => glutathione
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate
M00120 Coenzyme A biosynthesis, pantothenate => CoA
M00121 Heme biosynthesis, glutamate => heme
M00122 Cobalamin biosynthesis, cobinamide => cobalamin
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin
M00124 Pyridoxal biosynthesis, erythrose-4P => pyridoxal-5P
M00125 Riboflavin biosynthesis, GTP => riboflavin/FMN/FAD
M00126 Tetrahydrofolate biosynthesis, GTP => THF
M00127 Thiamine biosynthesis, AIR => thiamine-P/thiamine-2P
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone
M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA
M00136 GABA biosynthesis, prokaryotes, putrescine => GABA
M00137 Flavanone biosynthesis, phenylalanine => naringenin
M00138 Flavonoid biosynthesis, naringenin => pelargonidin
M00140 C1-unit interconversion, prokaryotes
M00141 C1-unit interconversion, eukaryotes
M00142 NADH:ubiquinone oxidoreductase, mitochondria
M00143 NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
M00144 NADH:quinone oxidoreductase, prokaryotes
M00145 NAD(P)H:quinone oxidoreductase, chloroplasts and cyanobacteria
M00146 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex
M00147 NADH dehydrogenase (ubiquinone) 1 beta subcomplex
M00148 Succinate dehydrogenase (ubiquinone)
M00149 Succinate dehydrogenase, prokaryotes
M00150 Fumarate reductase, prokaryotes
M00151 Cytochrome bc1 complex respiratory unit
M00152 Cytochrome bc1 complex
M00153 Cytochrome bd ubiquinol oxidase
M00154 Cytochrome c oxidase
M00155 Cytochrome c oxidase, prokaryotes
M00156 Cytochrome c oxidase, cbb3-type
M00157 F-type ATPase, prokaryotes and chloroplasts
M00158 F-type ATPase, eukaryotes
M00159 V/A-type ATPase, prokaryotes
M00160 V-type ATPase, eukaryotes
M00161 Photosystem II
M00162 Cytochrome b6f complex
M00163 Photosystem I
M00165 Reductive pentose phosphate cycle (Calvin cycle)
M00166 Reductive pentose phosphate cycle, ribulose-5P => glyceraldehyde-3P
M00167 Reductive pentose phosphate cycle, glyceraldehyde-3P => ribulose-5P
M00168 CAM (Crassulacean acid metabolism), dark
M00169 CAM (Crassulacean acid metabolism), light
M00170 C4-dicarboxylic acid cycle, phosphoenolpyruvate carboxykinase type
M00171 C4-dicarboxylic acid cycle, NAD - malic enzyme type
M00172 C4-dicarboxylic acid cycle, NADP - malic enzyme type
M00173 Reductive citrate cycle (Arnon-Buchanan cycle)
M00174 Methane oxidation, methanotroph, methane => formaldehyde
M00175 Nitrogen fixation, nitrogen => ammonia
M00176 Assimilatory sulfate reduction, sulfate => H2S
M00177 Ribosome, eukaryotes
M00178 Ribosome, bacteria
M00179 Ribosome, archaea
M00180 RNA polymerase II, eukaryotes
M00181 RNA polymerase III, eukaryotes
M00182 RNA polymerase I, eukaryotes
M00183 RNA polymerase, bacteria
M00184 RNA polymerase, archaea
M00185 Sulfate transport system
M00186 Tungstate transport system
M00188 NitT/TauT family transport system
M00189 Molybdate transport system
M00190 Iron(III) transport system
M00191 Thiamine transport system
M00192 Putative thiamine transport system
M00193 Putative spermidine/putrescine transport system
M00194 Maltose/maltodextrin transport system
M00196 Raffinose/stachyose/melibiose transport system
M00197 Putative fructooligosaccharide transport system
M00198 Putative sn-glycerol-phosphate transport system
M00199 L-Arabinose/lactose transport system
M00200 Putative sorbitol/mannitol transport system
M00201 alpha-Glucoside transport system
M00202 Oligogalacturonide transport system
M00204 Trehalose/maltose transport system
M00205 N-Acetylglucosamine transport system
M00206 Cellobiose transport system
M00207 Putative multiple sugar transport system
M00208 Glycine betaine/proline transport system
M00209 Osmoprotectant transport system
M00210 Phospholipid transport system
M00211 Putative ABC transport system
M00212 Ribose transport system
M00213 L-Arabinose transport system
M00214 Methyl-galactoside transport system
M00215 D-Xylose transport system
M00216 Multiple sugar transport system
M00217 D-Allose transport system
M00218 Fructose transport system
M00219 AI-2 transport system
M00220 Rhamnose transport system
M00221 Putative simple sugar transport system
M00222 Phosphate transport system
M00223 Phosphonate transport system
M00224 Fluoroquinolone transport system
M00225 Lysine/arginine/ornithine transport system
M00226 Histidine transport system
M00227 Glutamine transport system
M00229 Arginine transport system
M00230 Glutamate/aspartate transport system
M00231 Octopine/nopaline transport system
M00232 General L-amino acid transport system
M00233 Glutamate transport system
M00234 Cystine transport system
M00235 Arginine/ornithine transport system
M00236 Putative polar amino acid transport system
M00237 Branched-chain amino acid transport system
M00238 D-Methionine transport system
M00239 Peptides/nickel transport system
M00240 Iron complex transport system
M00241 Vitamin B12 transport system
M00242 Zinc transport system
M00243 Manganese/iron transport system
M00244 Putative zinc/manganese transport system
M00245 Cobalt/nickel transport system
M00246 Nickel transport system
M00247 Putative ABC transport system
M00249 Capsular polysaccharide transport system
M00250 Lipopolysaccharide transport system
M00251 Teichoic acid transport system
M00252 Lipooligosaccharide transport system
M00253 Sodium transport system
M00254 ABC-2 type transport system
M00255 Lipoprotein-releasing system
M00256 Cell division transport system
M00258 Putative ABC transport system
M00259 Heme transport system
M00260 DNA polymerase III complex, bacteria
M00261 DNA polymerase alpha / primase complex
M00262 DNA polymerase delta complex
M00263 DNA polymerase epsilon complex
M00264 DNA polymerase II complex, archaea
M00265 PTS system, glucose-specific II component
M00266 PTS system, maltose/glucose-specific II component
M00267 PTS system, N-acetylglucosamine-specific II component
M00268 PTS system, alpha-glucoside-specific II component
M00269 PTS system, sucrose-specific II component
M00270 PTS system, trehalose-specific II component
M00271 PTS system, beta-glucoside-specific II component
M00272 PTS system, beta-glucoside (arbutin/salicin/cellobiose)-specific II component
M00273 PTS system, fructose-specific II component
M00274 PTS system, mannitol-specific II component
M00275 PTS system, cellobiose-specific II component
M00276 PTS system, mannose-specific II component
M00279 PTS system, galactitol-specific II component
M00280 PTS system, glucitol/sorbitol-specific II component
M00283 PTS system, ascorbate-specific II component
M00284 Origin recognition complex
M00285 MCM complex
M00286 GINS complex
M00288 RPA complex
M00289 RF-C complex
M00290 Holo-TFIIH complex
M00291 MRN complex
M00292 MRX complex
M00293 DNA polymerase zeta complex
M00294 DNA polymerase gamma complex
M00295 BRCA1-associated genome surveillance complex (BASC)
M00296 BER complex
M00297 DNA-PK complex
M00298 Multidrug/hemolysin transport system
M00299 Spermidine/putrescine transport system
M00300 Putrescine transport system
M00301 Mannopine transport system
M00302 2-Aminoethylphosphonate transport system
M00303 PTS system, N-acetylmuramic acid-specific II component
M00305 PTS system, 2-O-A-mannosyl-D-glycerate-specific II component
M00306 PTS system, fructose-specific II-like component
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA
M00308 Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glycerate-3P
M00309 Non-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate
M00316 Manganese transport system
M00317 Manganese/iron transport system
M00319 Manganese/zinc/iron transport system
M00320 Lipopolysaccharide export system
M00321 Bicarbonate transport system
M00322 Neutral amino acid transport system
M00323 Urea transport system
M00324 Dipeptide transport system
M00325 alpha-Hemolysin/cyclolysin transport system
M00326 RTX toxin transport system
M00328 Hemophore/metalloprotease transport system
M00330 Adhesin protein transport system
M00331 Type II general secretion pathway
M00332 Type III secretion system
M00333 Type IV secretion system
M00334 Type VI secretion system
M00335 Sec (secretion) system
M00336 Twin-arginine translocation (Tat) system
M00337 Immunoproteasome
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine
M00339 RaxAB-RaxC type I secretion system
M00340 Proteasome, 20S core particle
M00341 Proteasome, 19S regulatory particle (PA700)
M00342 Bacterial proteasome
M00343 Archaeal proteasome
M00344 Formaldehyde assimilation, xylulose monophosphate pathway
M00345 Formaldehyde assimilation, ribulose monophosphate pathway
M00346 Formaldehyde assimilation, serine pathway
M00348 Glutathione transport system
M00349 Microcin C transport system
M00350 Capsaicin biosynthesis, L-Phenylalanine => Capsaicin
M00351 Spliceosome, U1-snRNP
M00352 Spliceosome, U2-snRNP
M00353 Spliceosome, Prp19/CDC5L complex
M00354 Spliceosome, U4/U6.U5 tri-snRNP
M00355 Spliceosome, 35S U5-snRNP
M00356 Methanogenesis, methanol => methane
M00357 Methanogenesis, acetate => methane
M00358 Coenzyme M biosynthesis
M00359 Aminoacyl-tRNA biosynthesis, eukaryotes
M00360 Aminoacyl-tRNA biosynthesis, prokaryotes
M00361 Nucleotide sugar biosynthesis, eukaryotes
M00362 Nucleotide sugar biosynthesis, prokaryotes
M00364 C10-C20 isoprenoid biosynthesis, bacteria
M00365 C10-C20 isoprenoid biosynthesis, archaea
M00366 C10-C20 isoprenoid biosynthesis, plants
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes
M00368 Ethylene biosynthesis, methionine => ethylene
M00371 Castasterone biosynthesis, campesterol => castasterone
M00372 Abscisic acid biosynthesis, beta-carotene => abscisic acid
M00373 Ethylmalonyl pathway
M00374 Dicarboxylate-hydroxybutyrate cycle
M00375 Hydroxypropionate-hydroxybutylate cycle
M00376 3-Hydroxypropionate bi-cycle
M00377 Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
M00378 F420 biosynthesis
M00379 SCF-MET30 complex
M00380 SCF-BTRC complex
M00381 SCF-SKP2 complex
M00382 SCF-FBS complex
M00383 ECV complex
M00384 Cul3-SPOP complex
M00385 Cul4-DDB1-DDB2 complex
M00386 Cul4-DDB1-CSA complex
M00387 SCF-FBW7 complex
M00388 ECS complex
M00389 APC/C complex
M00390 Exosome, archaea
M00391 Exosome, eukaryotes
M00392 Ski complex
M00393 TRAMP complex
M00394 RNA degradosome
M00395 Decapping complex
M00396 Lsm 2-8 complex
M00397 Lsm 1-7 complex
M00398 Sm core complex
M00399 Cap binding complex
M00400 p97-Ufd1-Npl4 complex
M00401 Sec61 complex
M00402 Translocon-associated protein (TRAP) complex
M00403 HRD1/SEL1 ERAD complex
M00404 COPII complex
M00405 THC complex
M00406 TREX complex
M00407 SCF-CDC4 complex
M00408 ESCRT-0 complex
M00409 ESCRT-I complex
M00410 ESCRT-II complex
M00411 SCF-GRR1 complex
M00412 ESCRT-III complex
M00413 FA core complex
M00414 Bloom's syndrome complex
M00415 Fatty acid biosynthesis, elongation, endoplasmic reticulum
M00417 Cytochrome o ubiquinol oxidase
M00418 Toluene degradation, anaerobic, toluene => benzoyl-CoA
M00422 Acetyl-CoA pathway, CO2 => acetyl-CoA
M00423 Molybdate/tungstate transport system
M00424 Shelterin complex
M00425 H/ACA ribonucleoprotein complex
M00426 Survival motor neuron (SMN) complex
M00427 Nuclear pore complex
M00428 eIF4F complex
M00429 Competence-related DNA transformation transporter
M00430 Exon junction complex (EJC)
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
M00434 PhoR-PhoB (phosphate starvation response) two-component regulatory system
M00435 Taurine transport system
M00436 Sulfonate transport system
M00438 Nitrate/nitrite transport system
M00439 Oligopeptide transport system
M00440 Nickel transport system
M00442 Putative hydroxymethylpyrimidine transport system
M00443 SenX3-RegX3 (phosphate starvation response) two-component regulatory system
M00444 PhoQ-PhoP (magnesium transport) two-component regulatory system
M00445 EnvZ-OmpR (osmotic stress response) two-component regulatory system
M00446 RstB-RstA two-component regulatory system
M00447 CpxA-CpxR (envelope stress response) two-component regulatory system
M00448 CssS-CssR (secretion stress response) two-component regulatory system
M00449 CreC-CreB (phosphate regulation) two-component regulatory system
M00450 BaeS-BaeR (envelope stress response) two-component regulatory system
M00451 BasS-BasR (antimicrobial peptide resistance) two-component regulatory system
M00452 CusS-CusR (copper tolerance) two-component regulatory system
M00453 QseC-QseB (quorum sensing) two-component regulatory system
M00454 KdpD-KdpE (potassium transport) two-component regulatory system
M00455 TorS-TorR (TMAO respiration) two-component regulatory system
M00456 ArcB-ArcA (anoxic redox control) two-component regulatory system
M00457 TctE-TctD (tricarboxylic acid transport) two-component regulatory system
M00458 ResE-ResD (aerobic and anaerobic respiration) two-component regulatory system
M00459 VicK-VicR (cell wall metabolism) two-component regulatory system
M00460 MprB-MprA (maintenance of persistent infection) two-component regulatory system
M00461 MtrB-MtrA (osmotic stress response) two-component regulatory system
M00462 PrrB-PrrA (intracellular multiplication) two-component regulatory system
M00466 NblS-NblR (photosynthesis) two-component regulatory system
M00467 SasA-RpaAB (circadian timing mediating) two-component regulatory system
M00471 NarX-NarL (nitrate respiration) two-component regulatory system
M00472 NarQ-NarP (nitrate respiration) two-component regulatory system
M00473 UhpB-UhpA (hexose phosphates uptake) two-component regulatory system
M00474 RcsC-RcsD-RcsB (capsule synthesis) two-component regulatory system
M00475 BarA-UvrY (central carbon metabolism) two-component regulatory system
M00477 EvgS-EvgA (acid and drug tolerance) two-component regulatory system
M00478 DegS-DegU (multicellular behavior control) two-component regulatory system
M00479 DesK-DesR (membrane lipid fluidity regulation) two-component regulatory system
M00481 LiaS-LiaR (cell wall stress response) two-component regulatory system
M00483 NreB-NreC (dissimilatory nitrate/nitrite reduction) two-component regulatory system
M00485 KinABCDE-Spo0FA (sporulation control) two-component regulatory system
M00486 CitA-CitB (citrate fermentation) two-component regulatory system
M00489 DctS-DctR (C4-dicarboxylate transport) two-component regulatory system
M00490 MalK-MalR (malate transport) two-component regulatory system
M00491 arabinogalactan oligomer/maltooligosaccharide transport system
M00492 LytS-LytR two-component regulatory system
M00493 AlgZ-AlgR (alginate production) two-component regulatory system
M00497 GlnL-GlnG (nitrogen regulation) two-component regulatory system
M00498 NtrY-NtrX (nitrogen regulation) two-component regulatory system
M00499 HydH-HydG (metal tolerance) two-component regulatory system
M00500 AtoS-AtoC (cPHB biosynthesis) two-component regulatory system
M00501 PilS-PilR (type 4 fimbriae synthesis) two-component regulatory system
M00502 GlrK-GlrR (amino sugar metabolism) two-component regulatory system
M00503 PgtB-PgtA (phosphoglycerate transport) two-component regulatory system
M00504 DctB-DctD (C4-dicarboxylate transport) two-component regulatory system
M00505 KinB-AlgB (alginate production) two-component regulatory system
M00506 CheA-CheYBV (chemotaxis) two-component regulatory system
M00507 ChpA-ChpB/PilGH (chemosensory) two-component regulatory system
M00509 WspE-WspRF (chemosensory) two-component regulatory system
M00511 PleC-PleD (cell fate control) two-component regulatory system
M00512 CckA-CtrA/CpdR (cell cycle control) two-component regulatory system
M00513 LuxQN/CqsS-LuxU-LuxO (quorum sensing) two-component regulatory system
M00514 TtrS-TtrR (tetrathionate respiration) two-component regulatory system
M00515 FlrB-FlrC (polar flagellar synthesis) two-component regulatory system
M00516 SLN1-YPD1-SSK1/SKN7 (osmosensing) two-component regulatory system
M00517 RpfC-RpfG (cell-to-cell signaling) two-component regulatory system
M00518 GlnK-GlnL (glutamine utilization) two-component regulatory system
M00519 YesM-YesN two-component regulatory system
M00520 ChvG-ChvI (acidity sensing) two-component regulatory system
M00523 RegB-RegA (redox response) two-component regulatory system
M00524 FixL-FixJ (nitrogen fixation) two-component regulatory system
M00525 Lysine biosynthesis, acetyl-DAP pathway, aspartate => lysine
M00526 Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
M00528 Nitrification, ammonia => nitrite
M00529 Denitrification, nitrate => nitrogen
M00530 Dissimilatory nitrate reduction, nitrate => ammonia
M00531 Assimilatory nitrate reduction, nitrate => ammonia
M00532 Photorespiration
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate
M00534 Naphthalene degradation, naphthalene => salicylate
M00535 Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
M00537 Xylene degradation, xylene => methylbenzoate
M00538 Toluene degradation, toluene => benzoate
M00539 Cumate degradation, p-cumate => 2-oxopent-4-enoate + 2-methylpropanoate
M00540 Benzoate degradation, cyclohexanecarboxylic acid =>pimeloyl-CoA
M00541 Benzoyl-CoA degradation, benzoyl-CoA => 3-hydroxypimeloyl-CoA
M00542 EHEC/EPEC pathogenicity signature, T3SS and effectors
M00543 Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate
M00544 Carbazole degradation, carbazole => 2-oxopent-4-enoate + anthranilate
M00545 Trans-cinnamate degradation, trans-cinnamate => acetyl-CoA
M00546 Purine degradation, xanthine => urea
M00548 Benzene degradation, benzene => catechol
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P
M00551 Benzoate degradation, benzoate => catechol / methylbenzoate => methylcatechol
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose
M00555 Betaine biosynthesis, choline => betaine
M00563 Methanogenesis, methylamine/dimethylamine/trimethylamine => methane
M00564 Helicobacter pylori pathogenicity signature, cagA pathogenicity island
M00565 Trehalose biosynthesis, D-glucose 1P => trehalose
M00567 Methanogenesis, CO2 => methane
M00568 Catechol ortho-cleavage, catechol => 3-oxoadipate
M00569 Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
M00571 AlgE-type Mannuronan C-5-Epimerase transport system
M00572 Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP
M00573 Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin
M00575 Pertussis pathogenicity signature 2, T1SS
M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate
M00580 Pentose phosphate pathway, archaea, fructose 6P => ribose 5P
M00581 Biotin transport system
M00582 Energy-coupling factor transport system
M00585 L-Cystine transport system
M00586 Putative amino-acid transport system
M00589 Putative lysine transport system
M00590 Erythritol transport system
M00591 Putative xylitol transport system
M00592 Inositol transport system
M00593 Inositol transport system
M00595 Thiosulfate oxidation by SOX complex, thiosulfate => sulfate
M00596 Dissimilatory sulfate reduction, sulfate => H2S
M00597 Anoxygenic photosystem II
M00599 Inositol-phosphate transport system
M00600 alpha-1,4-Digalacturonate transport system
M00601 Putative chitobiose transport system
M00602 Arabinosaccharide transport system
M00603 Putative aldouronate transport system
M00605 Glucose/mannose transport system
M00606 N,N'-Diacetylchitobiose transport system
M00607 Glycerol transport system
M00608 2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
M00609 Cysteine biosynthesis, methionine => cysteine
M00615 Nitrate assimilation
M00620 Incomplete reductive citrate cycle, acetyl-CoA => oxoglutarate
M00622 Nicotinate degradation, nicotinate => fumarate
M00623 Phthalate degradation, phthalate => protocatechuate
M00627 beta-Lactam resistance, Bla system
M00628 beta-Lactam resistance, AmpC system
M00630 D-Galacturonate degradation (fungi), D-galacturonate => glycerol
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P
M00633 Semi-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate-3P
M00634 Oleandomycin transport system
M00637 Anthranilate degradation, anthranilate => catechol
M00638 Salicylate degradation, salicylate => gentisate
M00639 Multidrug resistance, efflux pump MexCD-OprJ
M00641 Multidrug resistance, efflux pump MexEF-OprN
M00642 Multidrug resistance, efflux pump MexJK-OprM
M00643 Multidrug resistance, efflux pump MexXY-OprM
M00644 Vanadium resistance, efflux pump MexGHI-OpmD
M00645 Multidrug resistance, efflux pump SmeABC
M00646 Multidrug resistance, efflux pump AcrAD-TolC
M00647 Multidrug resistance, efflux pump AcrAB-TolC/SmeDEF
M00648 Multidrug resistance, efflux pump MdtABC
M00649 Multidrug resistance, efflux pump AdeABC
M00651 Vancomycin resistance, D-Ala-D-Lac type
M00655 AdeS-AdeR two-component regulatory system
M00660 Xanthomonas spp. pathogenicity signature, T3SS and effectors
M00663 SsrA-SsrB two-component regulatory system
M00668 Tetracycline resistance, TetA transporter
M00669 gamma-Hexachlorocyclohexane transport system
M00670 Mce transport system
M00673 Cephamycin C biosynthesis, aminoadipate + cycteine + valine => cephamycin C
M00676 PI3K-Akt signaling
M00677 Wnt signaling
M00678 Hedgehog signaling
M00679 BMP signaling
M00680 TGF-beta signaling
M00681 Activin signaling
M00682 Notch signaling
M00683 Hippo signaling
M00684 JAK-STAT signaling
M00685 Apoptotic machinery
M00686 Toll-like receptor signaling
M00687 MAPK (ERK1/2) signaling
M00688 MAPK (JNK) signaling
M00689 MAPK (p38) signaling
M00690 MAPK (ERK5) signaling
M00691 DNA damage-induced cell cycle checkpoints
M00692 Cell cycle - G1/S transition
M00693 Cell cycle - G2/M transition
M00694 cGMP signaling
M00695 cAMP signaling
M00696 Multidrug resistance, efflux pump AcrEF-TolC
M00697 Multidrug resistance, efflux pump MdtEF-TolC
M00698 Multidrug resistance, efflux pump BpeEF-OprC
M00699 Multidrug resistance, efflux pump AmeABC
M00700 Multidrug resistance, efflux pump AbcA
M00701 Multidrug resistance, efflux pump EmrAB
M00702 Multidrug resistance, efflux pump NorB
M00704 Tetracycline resistance, efflux pump Tet38
M00707 Multidrug resistance, MdlAB/SmdAB transporter
M00709 Macrolide resistance, MacAB-TolC transporter
M00711 Multidrug resistance, efflux pump MdtIJ
M00712 Multidrug resistance, efflux pump YkkCD
M00713 Fluoroquinolone resistance, efflux pump LfrA
M00714 Multidrug resistance, efflux pump QacA
M00715 Lincosamide resistance, efflux pump LmrB
M00717 Multidrug resistance, efflux pump NorA
M00718 Multidrug resistance, efflux pump MexAB-OprM
M00720 Multidrug resistance, efflux pump VexEF-TolC
M00721 Cationic antimicrobial peptide (CAMP) resistance, arnBCADTEF operon
M00722 Cationic antimicrobial peptide (CAMP) resistance, ethanolaminephosphotransferase EptA
M00723 Cationic antimicrobial peptide (CAMP) resistance, ethanolaminephosphotransferase EptB
M00724 Cationic antimicrobial peptide (CAMP) resistance, palmitoyl transferase PagP
M00725 Cationic antimicrobial peptide (CAMP) resistance, dltABCD operon
M00726 Cationic antimicrobial peptide (CAMP) resistance, lysyl-phosphatidylglycerol (L-PG) synthase MprF
M00727 Cationic antimicrobial peptide (CAMP) resistance, N-acetylmuramoyl-L-alanine amidase AmiA and AmiC
M00728 Cationic antimicrobial peptide (CAMP) resistance, envelope protein folding and degrading factors DegP and DsbA
M00729 Fluoroquinolone resistance, gyrase-protecting protein Qnr
M00736 Nocardicin A biosynthesis, L-pHPG + arginine + serine => nocardicin A
M00739 Cationic peptide transport system
M00740 Methylaspartate cycle
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
M00742 Aminoglycoside resistance, protease FtsH
M00743 Aminoglycoside resistance, protease HtpX
M00744 Cationic antimicrobial peptide (CAMP) resistance, protease PgtE
M00745 Imipenem resistance, repression of porin OprD
M00754 Nisin resistance, phage shock protein homolog LiaH
M00760 Erythromycin resistance, macrolide 2'-phosphotransferase I MphA
M00761 Undecaprenylphosphate alpha-L-Ara4N biosynthesis, UDP-GlcA => undecaprenyl phosphate alpha-L-Ara4N
M00762 Copper-processing system
M00763 Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
M00766 Streptomycin resistance, deactivating enzyme StrAB
M00767 Multidrug resistance, efflux pump OqxAB
M00768 Multidrug resistance, efflux pump GesABC
M00769 Multidrug resistance, efflux pump MexPQ-OpmE
M00770 PfeS-PfeR (enterobactin-dependent iron acquisition) two-component regulatory system
M00772 HupT-HupR (hydrogenase synthesis regulation) two-component regulatory system
M00778 Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
M00779 Dihydrokalafungin biosynthesis, octaketide => dihydrokalafungin
M00789 Rebeccamycin biosynthesis, tryptophan => rebeccamycin
M00790 Pyrrolnitrin biosynthesis, tryptophan => pyrrolnitrin
M00792 Manganese/zinc transport system
M00793 dTDP-L-rhamnose biosynthesis
M00797 dTDP-D-desosamine biosynthesis
M00798 dTDP-L-mycarose biosynthesis
M00799 dTDP-L-oleandrose biosynthesis
M00800 dTDP-L-megosamine biosynthesis
M00801 dTDP-L-olivose biosynthesis
M00802 dTDP-D-forosamine biosynthesis
M00803 dTDP-D-angolosamine biosynthesis
M00804 Complete nitrification, comammox, ammonia => nitrite => nitrate
M00806 PTS system, maltose-specific II component
M00809 PTS system, glucose-specific II component
M00813 Lantibiotic transport system
M00814 Acarbose biosynthesis, sedoheptulopyranose-7P => acarbose
M00815 Validamycin A biosynthesis, sedoheptulopyranose-7P => validamycin A
M00818 FusK-FusR (virulence regulation) two-component regulatory system
M00820 SagS-HptB-HsbR (swarming activity and biofilm formation) two-component regulatory system
M00821 Multidrug resistance, efflux pump TriABC-TolC
M00822 Multidrug resistance, efflux pump MexMN-OprM
M00823 Chlortetracycline biosynthesis, pretetramide => chlortetracycline
M00824 9-membered enediyne core biosynthesis, malonyl-CoA => 3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-ACP => 9-membered enediyne core
M00825 10-membered enediyne core biosynthesis, malonyl-CoA => 3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoyl-ACP => 10-membered enediyne core
M00827 C-1027 beta-amino acid moiety biosynthesis, tyrosine => 3-chloro-4,5-dihydroxy-beta-phenylalanyl-PCP
M00828 Maduropeptin beta-hydroxy acid moiety biosynthesis, tyrosine => 3-(2-chloro-3-hydroxy-4-methoxyphenyl)-3-hydroxypropanoyl-PCP
M00829 3,6-Dimethylsalicylyl-CoA biosynthesis, malonyl-CoA => 6-methylsalicylate => 3,6-dimethylsalicylyl-CoA
M00831 Kedarcidin 2-hydroxynaphthoate moiety biosynthesis, malonyl-CoA => 3,6,8-trihydroxy-2-naphthoate => 3-hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoyl-CoA
M00832 Kedarcidin 2-aza-3-chloro-beta-tyrosine moiety biosynthesis, azatyrosine => 2-aza-3-chloro-beta-tyrosyl-PCP
M00835 Pyocyanine biosynthesis, chorismate => pyocyanine
M00839 PdtaS-PdtaR two-component regulatory system
M00840 Tetrahydrofolate biosynthesis, mediated by ribA and trpF, GTP => THF
M00841 Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4
M00843 L-threo-Tetrahydrobiopterin biosynthesis, GTP => L-threo-BH4
M00844 Arginine biosynthesis, ornithine => arginine
M00845 Arginine biosynthesis, glutamate => acetylcitrulline => arginine
M00846 Siroheme biosynthesis, glutamate => siroheme
M00847 Heme biosynthesis, archaea, siroheme => heme
